Preclinical efficacy studies form the fundamental basis of research pharmacology and drug development.
In efficacy studies, the pharmacological effects of test compounds are investigated in laboratory animal models that have been developed to mimic the human disease. Such studies are key to predicting the success of treatment in humans with the disease.
Experimental set up and establishment of disease models
Innovative therapies often require flexible and client-tailored efficacy studies to demonstrate early proof of concept. Scantox offers experimental setup and establishment of disease models to meet specific sponsor requirements, focusing on pharmacological data collection and optimized animal welfare.
Scantox is a dedicated and highly qualified partner for preclinical efficacy studies. Our team is known for responsiveness and scientifically sound study designs, working in areas such as oncology, infection, inflammation, and diabetology, and dealing with rare diseases within the orphan drug indications.
Efficacy Models and Study Types
Scantox works with a variety of disease models in both rodents and non-rodents. Our experience includes establishing and validating customized models as well as developing new ones in collaboration with clients.
Examples of Our Current In-House Models
- Oncology models: syngeneic and xenografts
- Vaccine studies – infectious agents and cancer
- Infection studies, at BSL2 and BSL3
- Kidney damage/kidney transplant
- Blood coagulation disorders
- Inflammatory bowel disease
- Peritonitis
- Diabetes
- Wound healing
- Behavioral studies
- Rare diseases: blood diseases, liposomal storage disease, neurodegenerative diseases, and mitochondrial disorders
- Experimental surgery
- Veterinary vaccine development
For more information or discussions on other models, do not hesitate to contact us.